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Academic Publications 

-Albertus Magnus-

The aim of natural science is not simply to accept the statements of others, but to investigate the causes that are at work in nature.

1.         Samuels DS, Lybecker MC, Yang XF, Ouyang Z, Bourret TJ, Boyle WK, et al. Gene Regulation and Transcriptomics. Curr Issues Mol Biol. 2021;42:223-66. Epub 2020/12/11. doi: 10.21775/cimb.042.223. PubMed PMID: 33300497; PubMed Central PMCID: PMCPMC7946783.

2.         Boyle WK, Richards CL, Dulebohn DP, Zalud AK, Shaw JA, Lovas S, et al. DksA-dependent regulation of RpoS contributes to Borrelia burgdorferi tick-borne transmission and mammalian infectivity. PLoS Pathog. 2021;17(2):e1009072. Epub 2021/02/19. doi: 10.1371/journal.ppat.1009072. PubMed PMID: 33600418; PubMed Central PMCID: PMCPMC7924775.

3.         Shikiya RA, Kincaid AE, Bartz JC, Bourret TJ. Failure To Detect Prion Infectivity in Ticks following Prion-Infected Blood Meal. mSphere. 2020;5(5). Epub 2020/09/04. doi: 10.1128/mSphere.00741-20. PubMed PMID: 32878935; PubMed Central PMCID: PMCPMC7471009.

4.         Luedtke BE, Shaffer JJ, Monrroy E, Willicott CW, Bourret TJ. Molecular Detection of Spotted Fever Group Rickettsiae (Rickettsiales: Rickettsiaceae) in Dermacentor variabilis (Acari: Ixodidae) Collected Along the Platte River in South Central Nebraska. J Med Entomol. 2020;57(2):519-23. Epub 2019/10/03. doi: 10.1093/jme/tjz167. PubMed PMID: 31576408; PubMed Central PMCID: PMCPMC7530562.

5.         Boyle WK, Hall LS, Armstrong AA, Dulebohn DP, Samuels DS, Gherardini FC, et al. Establishment of an in vitro RNA polymerase transcription system: a new tool to study transcriptional activation in Borrelia burgdorferi. Sci Rep. 2020;10(1):8246. Epub 2020/05/20. doi: 10.1038/s41598-020-65104-y. PubMed PMID: 32427963; PubMed Central PMCID: PMCPMC7237435.

6.         Shaw JA, Bourret TJ. Digital PCR-based Competitive Index for High-throughput Analysis of Fitness in Salmonella. J Vis Exp. 2019;(147). Epub 2019/05/28. doi: 10.3791/59630. PubMed PMID: 31132072.

7.         Jackson-Litteken CD, Zalud AK, Ratliff CT, Latham JI, Bourret TJ, Lopez JE, et al. Assessing the Contribution of an HtrA Family Serine Protease During Borrelia turicatae Mammalian Infection. Front Cell Infect Microbiol. 2019;9:290. Epub 2019/08/29. doi: 10.3389/fcimb.2019.00290. PubMed PMID: 31456953; PubMed Central PMCID: PMCPMC6700303.

8.         Boyle WK, Groshong AM, Drecktrah D, Boylan JA, Gherardini FC, Blevins JS, et al. DksA Controls the Response of the Lyme Disease Spirochete Borrelia burgdorferi to Starvation. J Bacteriol. 2019;201(4). Epub 2018/11/28. doi: 10.1128/JB.00582-18. PubMed PMID: 30478087; PubMed Central PMCID: PMCPMC6351744.

9.         Bourret TJ, Boyle WK, Zalud AK, Valenzuela JG, Oliveira F, Lopez JE. The relapsing fever spirochete Borrelia turicatae persists in the highly oxidative environment of its soft-bodied tick vector. Cell Microbiol. 2019;21(2):e12987. Epub 2018/11/30. doi: 10.1111/cmi.12987. PubMed PMID: 30489694; PubMed Central PMCID: PMCPMC6454574.

10.       Shaw JA, Henard CA, Liu L, Dieckman LM, Vazquez-Torres A, Bourret TJ. Salmonella enterica serovar Typhimurium has three transketolase enzymes contributing to the pentose phosphate pathway. J Biol Chem. 2018;293(29):11271-82. Epub 2018/06/01. doi: 10.1074/jbc.RA118.003661. PubMed PMID: 29848552; PubMed Central PMCID: PMCPMC6065166.

11.       Marroquin-Guzman M, Hartline D, Wright JD, Elowsky C, Bourret TJ, Wilson RA. The Magnaporthe oryzae nitrooxidative stress response suppresses rice innate immunity during blast disease. Nat Microbiol. 2017;2:17054. Epub 2017/04/19. doi: 10.1038/nmicrobiol.2017.54. PubMed PMID: 28418377.

12.       Jacques BJ, Bourret TJ, Shaffer JJ. Role of Fly Cleaning Behavior on Carriage of Escherichia coli and Pseudomonas aeruginosa. J Med Entomol. 2017;54(6):1712-7. Epub 2017/10/06. doi: 10.1093/jme/tjx124. PubMed PMID: 28981669; PubMed Central PMCID: PMCPMC5850793.

13.       Bourret TJ, Liu L, Shaw JA, Husain M, Vazquez-Torres A. Magnesium homeostasis protects Salmonella against nitrooxidative stress. Sci Rep. 2017;7(1):15083. Epub 2017/11/10. doi: 10.1038/s41598-017-15445-y. PubMed PMID: 29118452; PubMed Central PMCID: PMCPMC5678156.

14.       Bourret TJ, Lawrence KA, Shaw JA, Lin T, Norris SJ, Gherardini FC. The Nucleotide Excision Repair Pathway Protects Borrelia burgdorferi from Nitrosative Stress in Ixodes scapularis Ticks. Front Microbiol. 2016;7:1397. Epub 2016/09/23. doi: 10.3389/fmicb.2016.01397. PubMed PMID: 27656169; PubMed Central PMCID: PMCPMC5013056.

15.       Troxell B, Zhang JJ, Bourret TJ, Zeng MY, Blum J, Gherardini F, et al. Pyruvate protects pathogenic spirochetes from H2O2 killing. PLoS One. 2014;9(1):e84625. Epub 2014/01/07. doi: 10.1371/journal.pone.0084625. PubMed PMID: 24392147; PubMed Central PMCID: PMCPMC3879313.

16.       Bourret TJ, Boylan JA, Lawrence KA, Gherardini FC. Nitrosative damage to free and zinc-bound cysteine thiols underlies nitric oxide toxicity in wild-type Borrelia burgdorferi. Mol Microbiol. 2011;81(1):259-73. Epub 2011/05/14. doi: 10.1111/j.1365-2958.2011.07691.x. PubMed PMID: 21564333; PubMed Central PMCID: PMCPMC3147059.

17.       Husain M, Jones-Carson J, Song M, McCollister BD, Bourret TJ, Vazquez-Torres A. Redox sensor SsrB Cys203 enhances Salmonella fitness against nitric oxide generated in the host immune response to oral infection. Proc Natl Acad Sci U S A. 2010;107(32):14396-401. Epub 2010/07/28. doi: 10.1073/pnas.1005299107. PubMed PMID: 20660761; PubMed Central PMCID: PMCPMC2922535.

18.       Henard CA, Bourret TJ, Song M, Vazquez-Torres A. Control of redox balance by the stringent response regulatory protein promotes antioxidant defenses of Salmonella. J Biol Chem. 2010;285(47):36785-93. Epub 2010/09/21. doi: 10.1074/jbc.M110.160960. PubMed PMID: 20851888; PubMed Central PMCID: PMCPMC2978607.

19.       Bourret TJ, Song M, Vazquez-Torres A. Codependent and independent effects of nitric oxide-mediated suppression of PhoPQ and Salmonella pathogenicity island 2 on intracellular Salmonella enterica serovar typhimurium survival. Infect Immun. 2009;77(11):5107-15. Epub 2009/09/10. doi: 10.1128/IAI.00759-09. PubMed PMID: 19737903; PubMed Central PMCID: PMCPMC2772513.

20.       Husain M, Bourret TJ, McCollister BD, Jones-Carson J, Laughlin J, Vazquez-Torres A. Nitric oxide evokes an adaptive response to oxidative stress by arresting respiration. J Biol Chem. 2008;283(12):7682-9. Epub 2008/01/17. doi: 10.1074/jbc.M708845200. PubMed PMID: 18198179.

21.       Bourret TJ, Porwollik S, McClelland M, Zhao R, Greco T, Ischiropoulos H, et al. Nitric oxide antagonizes the acid tolerance response that protects Salmonella against innate gastric defenses. PLoS One. 2008;3(3):e1833. Epub 2008/03/20. doi: 10.1371/journal.pone.0001833. PubMed PMID: 18350168; PubMed Central PMCID: PMCPMC2266805.

22.       McCollister BD, Myers JT, Jones-Carson J, Husain M, Bourret TJ, Vazquez-Torres A. N(2)O(3) enhances the nitrosative potential of IFNgamma-primed macrophages in response to Salmonella. Immunobiology. 2007;212(9-10):759-69. Epub 2007/12/19. doi: 10.1016/j.imbio.2007.09.019. PubMed PMID: 18086377; PubMed Central PMCID: PMCPMC2329578.

23.       McCollister BD, Bourret TJ, Gill R, Jones-Carson J, Vazquez-Torres A. Repression of SPI2 transcription by nitric oxide-producing, IFNgamma-activated macrophages promotes maturation of Salmonella phagosomes. J Exp Med. 2005;202(5):625-35. Epub 2005/09/01. doi: 10.1084/jem.20050246. PubMed PMID: 16129704; PubMed Central PMCID: PMCPMC2212872.

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